深度学习已在许多神经影像应用中有效。但是，在许多情况下，捕获与小血管疾病有关的信息的成像序列的数量不足以支持数据驱动的技术。此外，基于队列的研究可能并不总是具有用于准确病变检测的最佳或必需成像序列。因此，有必要确定哪些成像序列对于准确检测至关重要。在这项研究中，我们旨在找到磁共振成像（MRI）序列的最佳组合，以深入基于学习的肿瘤周围空间（EPV）。为此，我们实施了一个有效的轻巧U-NET，适用于EPVS检测，并全面研究了来自易感加权成像（SWI），流体侵入的反转恢复（FLAIR），T1加权（T1W）和T2的不同信息组合 - 加权（T2W）MRI序列。我们得出的结论是，T2W MRI对于准确的EPV检测最为重要，并且在深神经网络中掺入SWI，FLAIR和T1W MRI可能会使精度的提高无关。

This paper proposes a perception and path planning pipeline for autonomous racing in an unknown bounded course. The pipeline was initially created for the 2021 evGrandPrix autonomous division and was further improved for the 2022 event, both of which resulting in first place finishes. Using a simple LiDAR-based perception pipeline feeding into an occupancy grid based expansion algorithm, we determine a goal point to drive. This pipeline successfully achieved reliable and consistent laps in addition with occupancy grid algorithm to know the ways around a cone-defined track with an averaging speeds of 6.85 m/s over a distance 434.2 meters for a total lap time of 63.4 seconds.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Recently the focus of the computer vision community has shifted from expensive supervised learning towards self-supervised learning of visual representations. While the performance gap between supervised and self-supervised has been narrowing, the time for training self-supervised deep networks remains an order of magnitude larger than its supervised counterparts, which hinders progress, imposes carbon cost, and limits societal benefits to institutions with substantial resources. Motivated by these issues, this paper investigates reducing the training time of recent self-supervised methods by various model-agnostic strategies that have not been used for this problem. In particular, we study three strategies: an extendable cyclic learning rate schedule, a matching progressive augmentation magnitude and image resolutions schedule, and a hard positive mining strategy based on augmentation difficulty. We show that all three methods combined lead up to 2.7 times speed-up in the training time of several self-supervised methods while retaining comparable performance to the standard self-supervised learning setting.

Science tests competing theories or models by evaluating the similarity of their predictions against observational experience. Thus, how we measure similarity fundamentally determines what we learn. In machine learning and scientific modeling, similarity metrics are used as objective functions. A classic example being mean squared error, which is the optimal measure of similarity when errors are normally distributed and independent and identically distributed (iid). In many cases, however, the error distribution is neither normal nor iid, so it is left to the scientist to determine an appropriate objective. Here, we review how information theory can guide that selection, then demonstrate the approach with a simple hydrologic model.

The NASA Astrophysics Data System (ADS) is an essential tool for researchers that allows them to explore the astronomy and astrophysics scientific literature, but it has yet to exploit recent advances in natural language processing. At ADASS 2021, we introduced astroBERT, a machine learning language model tailored to the text used in astronomy papers in ADS. In this work we: - announce the first public release of the astroBERT language model; - show how astroBERT improves over existing public language models on astrophysics specific tasks; - and detail how ADS plans to harness the unique structure of scientific papers, the citation graph and citation context, to further improve astroBERT.

The meaningful use of electronic health records (EHR) continues to progress in the digital era with clinical decision support systems augmented by artificial intelligence. A priority in improving provider experience is to overcome information overload and reduce the cognitive burden so fewer medical errors and cognitive biases are introduced during patient care. One major type of medical error is diagnostic error due to systematic or predictable errors in judgment that rely on heuristics. The potential for clinical natural language processing (cNLP) to model diagnostic reasoning in humans with forward reasoning from data to diagnosis and potentially reduce the cognitive burden and medical error has not been investigated. Existing tasks to advance the science in cNLP have largely focused on information extraction and named entity recognition through classification tasks. We introduce a novel suite of tasks coined as Diagnostic Reasoning Benchmarks, DR.BENCH, as a new benchmark for developing and evaluating cNLP models with clinical diagnostic reasoning ability. The suite includes six tasks from ten publicly available datasets addressing clinical text understanding, medical knowledge reasoning, and diagnosis generation. DR.BENCH is the first clinical suite of tasks designed to be a natural language generation framework to evaluate pre-trained language models. Experiments with state-of-the-art pre-trained generative language models using large general domain models and models that were continually trained on a medical corpus demonstrate opportunities for improvement when evaluated in DR. BENCH. We share DR. BENCH as a publicly available GitLab repository with a systematic approach to load and evaluate models for the cNLP community.

流行模型是理解传染病的强大工具。但是，随着它们的大小和复杂性的增加，它们可以迅速在计算上棘手。建模方法的最新进展表明，替代模型可用于模拟具有高维参数空间的复杂流行模型。我们表明，深层序列到序列（SEQ2SEQ）模型可以作为具有基于序列模型参数的复杂流行病模型的准确替代物，从而有效地复制了季节性和长期传播动力学。一旦受过培训，我们的代理人可以预测场景比原始模型快几千倍，从而使其非常适合策略探索。我们证明，用博学的模拟器代替传统的流行模型有助于强大的贝叶斯推断。

使用自然语言处理方法自动汇总患者的主要进度注释中的主要问题，有助于与医院环境中的信息和认知超负荷作斗争，并可能为提供者提供计算机化的诊断决策支持。问题列表摘要需要一个模型来理解，抽象和生成临床文档。在这项工作中，我们提出了一项新的NLP任务，旨在在住院期间使用提供者进度注释的意见来在患者的日常护理计划中生成一系列问题。我们研究了两个最先进的SEQ2SEQ变压器体系结构T5和Bart的性能，以解决此问题。我们提供了一个基于公开可用的电子健康记录进度注释MART MART（MIMIC）-III中的公开电子健康记录进度注释的语料库。 T5和BART对通用域文本进行了培训，我们尝试了数据增强方法和域适应性预训练方法，以增加医学词汇和知识的接触。评估方法包括胭脂，Bertscore，嵌入句子上的余弦相似性以及对医学概念的F评分。结果表明，与基于规则的系统和通用域预训练的语言模型相比，具有领域自适应预训练的T5可实现显着的性能增长，这表明可以解决问题摘要任务的有希望的方向。

脑小血管疾病的成像标记提供了有关脑部健康的宝贵信息，但是它们的手动评估既耗时又受到实质性内部和间际变异性的阻碍。自动化评级可能受益于生物医学研究以及临床评估，但是现有算法的诊断可靠性尚不清楚。在这里，我们介绍了\ textIt {血管病变检测和分割}（\ textit {v textit {where valdo？}）挑战，该挑战是在国际医学图像计算和计算机辅助干预措施（MICCAI）的卫星事件中运行的挑战（MICCAI） 2021.这一挑战旨在促进大脑小血管疾病的小而稀疏成像标记的自动检测和分割方法的开发，即周围空间扩大（EPVS）（任务1），脑微粒（任务2）和预先塑造的鞋类血管起源（任务3），同时利用弱和嘈杂的标签。总体而言，有12个团队参与了针对一个或多个任务的解决方案的挑战（任务1 -EPVS 4，任务2 -Microbleeds的9个，任务3 -lacunes的6个）。多方数据都用于培训和评估。结果表明，整个团队和跨任务的性能都有很大的差异，对于任务1- EPV和任务2-微型微型且对任务3 -lacunes尚无实际的结果，其结果尤其有望。它还强调了可能阻止个人级别使用的情况的性能不一致，同时仍证明在人群层面上有用。